Quick Answer

The 2026 NCCI Medicare Policy Manual establishes coding rules to prevent improper Medicare Part B payments. It includes three edit types: PTP edits (prevent reporting incompatible procedure pairs), MUE edits (set maximum units per code per day), and AOC edits (ensure add-on codes pair with primary codes). The manual was updated January 1, 2026, with quarterly edit file updates continuing throughout the year.

Key Takeaways

  • 2026 Q1 NCCI edits released December 1, 2025—effective January 1, 2026
  • 675,000+ Practitioner PTP edits now in effect; updated quarterly
  • Only NCCI-associated modifiers bypass PTP edits—22, 76, 77 do NOT
  • MAI "2" MUE denials are absolute limits that cannot be appealed
  • Unbundling violations account for ~15% of audited coding errors
  • 90% of coding denials are preventable with proper NCCI compliance

What Is the NCCI Medicare Policy Manual?

The National Correct Coding Initiative (NCCI) is CMS's primary tool for preventing improper Medicare Part B payments. The NCCI Policy Manual explains the rationale behind these edits and guides correct coding practices.

Every claim submitted to Medicare goes through automated prepayment checks. NCCI systems analyze every code pair for the same patient, same date of service, same provider to determine if an edit exists. If it does, one code is denied.

$31.7B
Medicare FFS improper payments FY 2024
50%
Medicare claims processed inaccurately
90%
Coding denials are preventable

The Three Types of NCCI Edits

The 2026 NCCI Medicare Policy Manual establishes three edit types that work together to prevent inappropriate payments:

1. Procedure-to-Procedure (PTP) Edits

PTP edits prevent inappropriate payment of services that shouldn't be reported together. Each edit pairs two codes:

  • Column One code — Eligible for payment
  • Column Two code — Denied unless a clinically appropriate modifier is allowed and reported

The Correct Coding Modifier Indicator (CCMI) determines if modifiers can bypass the edit:

CCMI Meaning Can Modifiers Bypass?
0 Codes are never separately reportable No — edit cannot be bypassed
1 Clinical circumstances may justify separate reporting Yes — with proper documentation
9 Deletion date equals effective date Technical indicator only

2. Medically Unlikely Edits (MUEs)

MUEs set the maximum units of service (UOS) for a HCPCS/CPT code per beneficiary, per provider, per date of service. They reduce the Medicare Fee-For-Service error rate by catching impossible or improbable unit quantities.

The MUE Adjudication Indicator (MAI) determines how edits are applied and whether appeals are possible:

MAI Type How Applied Appeal?
1 Claim Line Edit Each line compared to MUE; modifiers may allow separate lines Yes
2 Absolute DOS Edit Policy-based absolute limit No
3 Clinical Benchmark DOS Edit All UOS summed and compared to MUE Yes
Critical: MAI "2" Edits Are Absolute

MAI "2" MUEs represent policy-based limits that cannot be overridden through appeals, medical review, or any other process. Even with supporting documentation, MACs cannot pay units exceeding these values. Always verify MAI values before submitting claims with high unit counts.

3. Add-on Code (AOC) Edits

AOC edits ensure add-on codes are only reported with designated primary codes. An add-on code describes a service performed in conjunction with another primary service by the same practitioner—it's rarely eligible for payment alone.

Add-on Code Example

CPT 11008 (Removal of prosthetic material or mesh, abdominal wall for infection) is an add-on code that can only be reported with specific primary codes like 10180 or 11004-11006. Reporting it alone will result in denial.

NCCI-Associated Modifiers That Bypass PTP Edits

Only specific modifiers can bypass PTP edits with CCMI "1." Using the wrong modifier—or using these modifiers without clinical justification—is a compliance violation.

Category Modifiers Usage
Anatomic E1-E4, FA, F1-F9, TA, T1-T9, LT, RT, LC, LD, RC, LM, RI Different anatomic sites
Global Surgery 24, 25, 57, 58, 78, 79 E&M services in global periods
Other 27, 59, 91, XE, XS, XP, XU Distinct services
Modifiers 22, 76, 77 Do NOT Bypass NCCI Edits

According to the AMA, a common coding error is assuming modifiers 22 (Increased Procedural Services), 76 (Repeat Procedure by Same Physician), and 77 (Repeat Procedure by Another Physician) can bypass NCCI edits. They cannot.

Specialty-Specific NCCI Coding Rules

The 2026 NCCI Manual includes specialty-specific guidance across 13 chapters. Here are key policies organized by specialty that commonly trigger denials.

🩺 Integumentary / Dermatology

  • ONE removal code per lesion only
  • Biopsy NOT separate with lesion removal
  • FNA: 1 UOS per lesion, not per pass
  • CPT 88342: ONE unit per Mohs specimen

🦴 Musculoskeletal / Orthopedics

  • CPT 20670/20680: ONE unit per site
  • Allografts: MUE = 1 regardless of levels
  • Arthrocentesis includes bursae
  • Includes all implants removed

❤️ Cardiovascular / Cardiology

  • Venous graft procurement INCLUDED
  • Cannula insertion is INTEGRAL
  • ONE code per dialysis circuit
  • Thrombolysis: MUE = 1 per day

🔬 Digestive / Gastroenterology

  • Surgical includes diagnostic scope
  • Same procedure = ONE code, ONE UOS
  • Dilation includes ALL strictures
  • Integral: venous access, oximetry

👁️ Ophthalmology

  • Cataract codes: MUTUALLY EXCLUSIVE
  • Iridectomy is INTEGRAL to cataract
  • Trichiasis: UOS = eye, not eyelid
  • Visual field NOT separate with blepharoplasty

📡 Radiology

  • Guidance: ONE UOS per encounter
  • Unit = encounter, not needle placements
  • Port images (77417): MUE = 1
  • Isodose plan: single UOS for all points

🧬 Pathology & Laboratory

  • Molecular path includes all prep steps
  • No microdissection for slide scraping
  • CPT 81455 NOT with 81445/81450
  • CPT 88291: MUE = 1 for all tests

🏃 Physical Medicine & Rehab

  • ONE OT eval per OT per DOS
  • ONE PT eval per PT per DOS
  • Cannot bill OT + PT eval together
  • No therapy overlap except 97010-97028

Stay Ahead of NCCI Policy Changes

Payer Policy Copilot tracks quarterly NCCI updates automatically. Denials360 catches coding errors before submission.

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How to Appeal NCCI Medicare Denials

When claims are denied based on NCCI edits, follow these guidelines:

  1. Verify the MAI indicator — Check if the MUE denial has MAI 1, 2, or 3. MAI 2 edits are absolute and cannot be appealed.
  2. Submit appeals to your MAC — Appeals go to your Medicare Administrative Contractor, NOT the NCCI contractor.
  3. Include clinical documentation — For MAI 1 and 3 MUEs, MACs may pay medically necessary UOS in excess of MUE value on appeal with proper documentation.
  4. Request edit reconsideration if needed — For systemic issues, email [email protected] with rationale for proposed edit changes.
Appeal Success Rates

According to Health Affairs research, 57% of Medicare Advantage claim denials are ultimately overturned on appeal. For NCCI-related denials with proper clinical documentation, overturn rates can be even higher—but MAI "2" edits remain absolute. Smart Appeals generates compliant appeal letters with proper clinical justification.

Common NCCI Coding Errors to Avoid

According to AAPC's 2026 Medicare analysis and industry data, these errors trigger the most NCCI-related denials:

Unbundling Violations

Industry data shows unbundling occurs in nearly 15% of audited charts. Common violations include:

  • Reporting multiple codes when one comprehensive code exists
  • Fragmenting procedures into components
  • Unbundling bilateral procedures (use modifier 50 with 1 UOS instead)
  • Reporting integral services separately (surgical access, wound closure, dressings)

Modifier Misuse

Missing modifier codes account for roughly 10% of surgical claim denials:

  • Using modifiers solely to bypass edits without clinical justification
  • Assuming modifiers 22, 76, 77 bypass NCCI edits (they don't)
  • Applying anatomic modifiers when procedures were on same site

MUE Violations

  • Reporting units exceeding MUE values without understanding MAI type
  • Failing to split claims appropriately for MAI "1" edits
  • Appealing MAI "2" edits (they're absolute—appeals waste resources)

Frequently Asked Questions

What are the three types of NCCI edits in the 2026 Medicare Policy Manual?
The 2026 NCCI Medicare Policy Manual includes three edit types: (1) Procedure-to-Procedure (PTP) edits that prevent payment for services that shouldn't be reported together, (2) Medically Unlikely Edits (MUEs) that set maximum units of service per code per day, and (3) Add-on Code (AOC) edits that ensure add-on codes are only reported with designated primary codes.
Which modifiers can bypass NCCI PTP edits?
Only NCCI-associated modifiers can bypass PTP edits with CCMI "1": Anatomic modifiers (E1-E4, FA, F1-F9, TA, T1-T9, LT, RT, LC, LD, RC, LM, RI), Global Surgery modifiers (24, 25, 57, 58, 78, 79), and Other modifiers (27, 59, 91, XE, XS, XP, XU). Important: Modifiers 22, 76, and 77 are NOT NCCI-associated and cannot bypass PTP edits.
What is the difference between MAI 1, MAI 2, and MAI 3 MUE edits?
MAI "1" (Claim Line Edit) compares each line to the MUE value and modifiers may allow separate lines. MAI "2" (Absolute DOS Edit) is a policy-based absolute limit that cannot be overridden through appeals. MAI "3" (Clinical Benchmark DOS Edit) sums all units of service and compares to the MUE. MAI 1 and 3 edits may be appealed; MAI 2 edits cannot.
Can MUE denials be appealed to Medicare?
It depends on the MUE Adjudication Indicator (MAI). MAI "1" and MAI "3" MUEs may be appealed to your Medicare Administrative Contractor (MAC) if additional units are medically necessary with proper documentation. MAI "2" MUEs are absolute limits based on policy and cannot be overridden through appeals under any circumstances.
When does CMS update NCCI edits?
CMS updates NCCI PTP and MUE edit files quarterly on January 1, April 1, July 1, and October 1. The NCCI Policy Manual is updated annually, effective January 1. The 2026 Q1 edits were posted December 1, 2025, effective January 1, 2026.
What is unbundling in medical coding?
Unbundling is reporting multiple CPT codes for individual parts of a procedure when a single comprehensive code exists. This violates NCCI rules and can result in claim denials, audits, and compliance issues. Examples include: fragmenting procedures into components, reporting integral services separately, and reporting bilateral procedures without modifier 50.
How do I report bilateral procedures under NCCI rules?
For bilateral procedures, report the procedure code once with modifier 50 and one unit of service (UOS). Do not report two separate lines with LT and RT modifiers unless specific payer instructions require it. Unbundling bilateral procedures by reporting two units without modifier 50 is a common NCCI violation.
Where can I look up current NCCI edits?
CMS publishes current edit files on the NCCI for Medicare page. The NCCI Policy Manual explains the rationale for edits. For automated tracking, solutions like Payer Policy Copilot monitor quarterly changes and alert you to relevant updates.

Reduce NCCI-Related Denials with AI

NCCI compliance isn't just about knowing the rules—it's about catching errors before claims go out. With quarterly updates adding hundreds of new edits, manual tracking is increasingly impractical.

AI-powered solutions can automatically flag potential NCCI violations, verify modifier appropriateness, and generate compliant appeals when denials do occur.

DR

DataRovers Team

DataRovers provides AI-powered denial management for healthcare RCM teams. Denials360 catches coding errors before submission, Smart Appeals automates compliant appeal generation, and Payer Policy Copilot tracks NCCI and payer policy changes. Learn more.